fig1

Figure 1. A visual summary of the mechanism detailed in the section of pathophysiology. Image adapted by authors from ref^[17,38]. tPA: Tissue plasmínogen activator; VCAM: vascular cell adhesion molecule; ICAM: intercellular adhesion molecule; Lyso-Gb3: globotriaosylsphingosine; ROS: reactive oxygen species; NO: nitric oxide; ANG: angiotensin; AT-1: angiotensin type 1 receptor; AT-2: angiotensin type 2 receptor; MPO: myeloperoxidase; RBC: red blood cells; WBC: white blood cells.